EFFICACY AND SAFETY OF IMMUNE CHECKPOINT INHIBITORS-COMBINED ANTIANGIOGENIC DRUGS IN THE TREATMENT OF HEPATOCELLULAR CARCINOMA: A SYSTEMATIC REVIEW AND META ANALYSIS

BackgroundHepatocellular carcinoma is a pathological type of liver cancer and accounts for the majority of primary liver cancers.We conducted a meta-analysis to evaluate the efficacy and safety of immune checkpoint read more inhibitors in combination with antiangiogenic drugs in the treatment of hepatocellular carcinoma.MethodsWe searched scientifi

The comet assay (also known as single-cell gel electrophoresis) is a technique for the detection of DNA damage at bushranger awning the level of the individual cell.It is a versatile, relatively simple to perform and sensitive method.Although most investigations make use of its ability to measure DNA single-strand breaks, modifications to the metho

IntroductionFusarioid fungi that cause damping-off and root diseases can result in significant losses to conifer crops produced in forest nurseries across the USA.These nurseries are vital to reforestation and forest restoration efforts.Understanding the diversity of Fusarioid fungi associated with damping-off aluminum lotion and root diseases of c

This study assessed eleven elements in 24 edible-podded peas, including sugar snap pea and snow pea genotypes aiming to identify promising parents for nutraceutical breeding.Elemental concentrations of pods (dry weight basis) were estimated through inductively coupled plasma-optical emission spectroscopy read more (ICP-OES).The ranges for these ele